SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8cc82d27156ea7c59f15db1c239533d5d80062dcd1fe8021f546dc15f2e9df94' 
  AND token = '2ITzz4VtvBEpBqeegeHXFSbhYvjplJQviQl79ZumYpU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}