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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4e49bd91f8def8c9b52f194f8d0c224f25d4e47f1f9e1e653735610975fcc150' 
  AND token = 'l5u70AMG/wypvZuOiqfzPEHeQ3wW6Lr+FchRiIsNIdY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}