SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4ce44689673abfd8685eced2383a85c3694586753b99ab5e7002f65e21494477' 
  AND token = 'GXF7NQ+DNg7sS6C4T33cj11MJfk1q8HbY1BGNRrqx7Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}