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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4c987fb789cc4b50a32cbeff34ace77455e48e24220f28db50d6fb437b37a193' 
  AND token = '9fgib9mC+m9Q7MKTkDxxmWelu2Ihpc5oOzBLeBe3V70=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00072

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}