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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4b456d06ac466a0475b7f345f3c6ee2dda17dee3c2b7c7770f01328770a701f2' 
  AND token = 'FTydz5p93mKLzg5kpC3CoIk5HRiQ+DjuA6KD8VNBD7U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}