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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '753f3ab14c29c1c4fce272156af1e2bb8b2034db1f64240a98bb6e952529da6e' 
  AND token = 'W/nzpnSt3gkGRRS1Y67alA4xOFus8+wZIevrVicD9Xw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}