SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'abe754edcf2a35cb3eb137c4ccc014da5fd468cb9e9119d28ed0287d0f44dfdb' 
  AND token = 'iNgWoCjJq+iyx2dZPp1fz7EUoPfVeAM6Bmg2IwHMJd8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}