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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '89f02b95bcc3a25df479bdf78ffcdd205b48a571f0d256f01472139023ef06ea' 
  AND token = 'RsuDKi96Gl+LHfazVcd4aBrtMJNuSMdT3KrbrEg/9lA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}