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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'dc8c453fd709132507cb935988459881add42b607e7fdda5a40f31d04ecb001b' 
  AND token = 'Z7DFF0sqzTrcwYAB0/ky0Kg63EuxLc7e1Dbq4TB9lyY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}