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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '718f137aa28247136fabf1cdf7c797fe423dd7a9ff95b6543a38a486894dd711' 
  AND token = 'NTx+5UGVUApx4GZA7W8hSmbnui2L9ST4pxGQjIQYyoY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}