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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5b8f54e88a3bc7305d2639cb591c319b63b5d34a061d34c336a421362cc2e827' 
  AND token = 'Jxc0b0k5bCDsjRe77R7gLMNXuPLWXsFPxGodnXfWkgI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}