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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f2780309accba8aba98fd6ef2a4bd6ad1caf5a9c12e150214d49bd180f1af219' 
  AND token = 'KgtKqIEuuoQNEK54OEYFW646759jQ4OMYn5YgKOX8IM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}