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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '593497509b174da02e2e605f3981b4d04dc2f54129350b8f05edc586b57c7bdf' 
  AND token = 'EoncLaZg3beuHoC4258qeZsSDdxVCSHgnbZmaTdAak4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}