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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2e61257555e87ba1915801a6f9fe6df89823f57bdcb65525a082e8e6f03650aa' 
  AND token = 'cnhj5SIF/9nk9qe7C7YYbuPWWilfXHQ+A9TgYNQTg1c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}