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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '426d65d29db0e3c30a0b821e59bdf3542f649abfd722ebdd4acd01b3e2709620' 
  AND token = 'E4kJK/kdxdOsO1z8LAq3Z6vNl6pQrDb7Lz1VGRgmlDU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}