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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2c2d5aea37415d680d08c78be18c889d221196a281b955688639968d0ee7e478' 
  AND token = 'FGIUTKfXNNMT/nl0OhgK44RAjmRxE571DXtOouypGKM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}