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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f349bd1f046d3a23c4bc2d5314d318d915a5272a17b219edb627c18b25ee3923' 
  AND token = 'KWWJ4E7r+9A9XanymT0mMVCO9A9a+N2iIIeIAGDSJu8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}