SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e7ca8a1cd5f75da72294b74d8fd26c0ca4fcce002523deb1ad38d2e54dcf3abf' 
  AND token = 'DphFsg91zzlYUR1qVEmOQZ378HLH5T1STbLuR4DjEyI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}