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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '233be25cbabfc336575fd244b4aeddf6f495f7d618cdf68757a160b7d1ed516f' 
  AND token = '4vVXX4K0Z2LFY2m/YbXjzmzreTeMHSkdX3VeQYIrt+Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}