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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0500565ec889d6628d435ff60c2a62bc15758453a734559781768f96161dfabf' 
  AND token = '6DKdA9Nd2xy/a5VpM6x12yWN3f7Y7EaZ85HTu4P/Yo4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}