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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6e6b7c1b8a34186b7a9fbdd8d22551ffd7755dd94993eec8c48d5c47a1175644' 
  AND token = '5RAC/GFIR4v2SzW0bcZ5f3y6pkEyY2DjTOEMtph+3jk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}