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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a667cf4e788b2cf036a4c2ec36d9d47ae7102f4a2a6b3a27ffcf6839fd1bb221' 
  AND token = 'G8qAiSmXAZgEbK1RcsBHVDTqUiw6hlhVxlriqrQ3RbY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}