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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a2d48d8e6be74632218c7be14ed844f3af6d6b09150c7209d9f6084d3cfcd622' 
  AND token = '2NAzs8X6cDLX5Iut9BK1OcPJLIm6RNh7NSM6l5C+HMs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}