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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '318f81aa284c40a03c28c7867c514b24f1a26e19242e3151981d373823f621bd' 
  AND token = 'BlMY3o4VslNrlo6fS5PjFcdHmdDpqLZ/i3S2Mq74zdo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}