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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f381c9a6c2118f56b60e54d954a6b9e3b8e9ed8ba610c1bc4d284de57174fee5' 
  AND token = 'rTv3RkURvfIiFcXV0jx/VPxEjSiHiPhm3yrPogZD2fM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}