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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '53e1b21e0cf88080529c294d2436f7ae4e3b4e6cd55de4ed3a15b1a888c3e9f9' 
  AND token = 'PUwbE697FK1lxqCDVrM60+VBlIZTxjlnie3OH4IRk3c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}