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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '70e1d4eb2fe2bf24866ff00bdcbc44a2ee20264f7e796e79a1fa38850a36a5d5' 
  AND token = 'yUpINYFOJRmrIvsPgYrknNAI3qIurhpt+kaNOdgNsMY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}