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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b78756075d89b6da34aee19a60a5c66d70af3256a2eb05ef68de0774e68f5fd3' 
  AND token = 'JvRphfQ5iOrqqBW1Krr9m7kO7OFwNxBl4I5ux9sgCw8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}