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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '80108b0d29b050288bad9b241a89f8e176ebd198d9ee26121188f198bf88af54' 
  AND token = 'rhIL9dVu9wtNigYBtGOCxk+e6VfYgsxRq/VW/XMiWzQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}