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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ea3b01f6f245bbacc34c0f788463e71e3cad69d3da16899108e9b533ed74cfb6' 
  AND token = '8CMHqp/mPtkxG/8Gtqi+mDyNeCMwJGP3cTGTkicWVhM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}