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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6acc146962850911ea18e26046db963e1c74d52c55bd1779e781ee0e6a96bae2' 
  AND token = 'OQXjlZ50+OB4O6aGSlaxnoC1UacBHXlAgWbtuUfmoYw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}