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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cafb5512158bb34ce5844c2b12143809d818282b1068c19033808ac8f3d00b88' 
  AND token = 'jgOAiHYiFk5JZTX+PMOqwls7g9sLK5z79r58WxN2tPQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}