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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7ef67ce90496029b56e629b7fd07aa1ca90e365c5d8ac2654f8e78b8074466cb' 
  AND token = 'uMcjCdrGSHPBJH8URtQA87NifDUuOXUYnjd1fa44KuE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}