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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a27be73f76fd0f949a76c45663371c1704c9b04e9274807f26d989616506258d' 
  AND token = 'EmDHqOC45KOXY/Is9HaST9lfVu0cCPMu+74IMglQ1Tc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}