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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b5641bb01bfeb76a27357fe9b79395f04954b1c127961d62f2b7c547fa8fa2f8' 
  AND token = 'MLHeGX8/7aiK9mcK6vTxmuCCuzcWxi/eX9IDL4vAYYI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}