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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6a221b002b3e471d67b53f8daee2598d91eb738a593a76016c28a75d7b93c943' 
  AND token = 'l29lN3vUrCTMpODgYwZl1VH8OmY/LFfBekYWi+ik3io=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}