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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '478d88bbe8417a36d5e6f53fd36491cb1da5d2826d1160dbdf4a895e93d2f800' 
  AND token = 'IuFifTEzsfYHg4yNsFrO1a3QKy6TOY+LUarD+yVSuHY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}