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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f8e110bd198447d7dd2406973ece1475daab23d02b1abd2efbfadb27e3a76b77' 
  AND token = 'xoLhP8e8Ws5fhPp2/ct3DHrEsDXOgzYILbXo1RkeJPM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}