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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '49c92b8c5b636795f6229f6584348b581b7abe99ae84b6f3da661730931301e3' 
  AND token = 'XzrO7Dl067nUi/HWqK9f7V378o07muIBMzsWltxb7g8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}