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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8ff5535c2a2073b6d3681b1468ce0f05e53206d630c7fec5d9a7996995122287' 
  AND token = '+FfnyfrgpHNsL5l94XNSXUAajdY4mROX6kEq8258uSM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}