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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8808dd3ca1bb710deafa53384325994de6a111919ea362160e7a84e7ecda7ca0' 
  AND token = 'RDywp7MJOcEe2MpayjyL0kY5mFCZcfgFlgTpTx3qAVA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}