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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e9e75f0396f0e49883e94bf7c771d820f744b3af9e3e2bd39bf1b49e006cc173' 
  AND token = 'tTbTY8FK75uJp1UXj4T/TkRyzTgFnyUd5gJhY4RsD2k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}