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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2eaf50b5799b7524593b5538dc1e0eda1f07d6c5fedbccd0fde46d0cae774607' 
  AND token = 'Iw/0LKIvdP7Leu5afyr9jXuBTrRX++YhCHKdPbHX8cM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}