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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cb80334b2d72d37857e4f4d79716ebe1b82c3b410e69b4cc8173db54127ca04b' 
  AND token = 'T+ygMcECci3J6EOSN3j95fKK4OVOqSANcjqrH07IwQs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}