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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0f7c865758f765e70d440dfbc82581351197c1bc4e9a995e58a8d1aa78b0e29f' 
  AND token = 'ceHoCyDkSCT0MR9n43X5/2TUDTOfrK4JWr2WekTCDGY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}