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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ac00d44e699d2533ee68ba70c97b3e0944fa8ca9df280e03eee40412ded85f52' 
  AND token = '7xuQ4NlCaaHScewpWuyeBdWC3JMWyZ41nQVgFkp7xgY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}