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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd444ad21622e3e4f1d4fc428ca1fee7b60a64970113fa9128a19caf59bbdd055' 
  AND token = 'HV1Zy2Ev0HGLvmXdUlCHpEMZMoPYYc4et6qQDgG1u5w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}