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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e74380769814f202dbe38a489a7b9afcbbe01b9ec41f590c49a764b2dc977ddf' 
  AND token = 'AKx7YIoakpszsTibmvFylmD2J+zqjtobv05/Kj7RcbQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}