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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8fcf79ccfd55d4d932c30b26dc327bf003df320382038b3cacde56650d1c1162' 
  AND token = 'RU7G2nXmNeU+QvY8URtS70gp5F/OqTBGPHLGYoK2+aA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}