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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '61c65d8b2016c083ee12177cb81aa4b0c02a2633777bfd36987c72f3677f1440' 
  AND token = 'zXoRIEkk4Xm0DpbT1+jLvt/MRT9vXTgtygHhUXVZumA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}